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However, in another study using an INS-1 832/3 β cell line, the metformin-induced upregulation of GLP-1R mRNA expression was mediated via peroxisome proliferator-activated receptor-α rather than AMPK pathway 30
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This research topic will feature reviews on the structural biology, pharmacology and clinical development of GLP-1 (and related peptides) receptor agonists and multi-agonists also targeting other receptors, and of DPP-4 inhibitors
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